Atividade antibacteriana de méis de meliponíneos obtidos de diferentes regiões do estado do Paraná (Brasil)

Abstract

Due to the irrational use of certain compounds, as ampicillin, cephalexin and others, bacteria progressively have been developing drug resistance, leading to studies for new antimicrobial activity formulations, analyzing different natural products like honey. Meliponines, also known as stingless bees, develop a distinctive honey with particular sensory and physicochemical characteristics. This study aims to evaluate the honey antimicrobial activity from Tetragonisca angustula (JATAI), Melipona quadrifasciata (MANDAÇAIA) e Scaptotrigona bipunctata (TUBUNA), from different regions of Paraná state (Brazil) on the bacteria Escherichia coli, Pseudomonas aeruginosa, Salmonella Typhymurium, Staphylococcus aureus, whose Minimum Inhibitory Concentration (MIC) by microdilution in broth, proposed by the Clinical and Laboratory Standards Institute (CLSI) was verified. The different honey samples analyzed showed antimicrobial activity in relation to bacteria proposals. Jatai honey stood out being the best antibacterial agent when compared to other kinds of honey investigated, due to its action against all bacteria tested. However, the samples of honey from Tubuna expressed the lowest performance among the analyzed honeys, where there was growth of S. aureus and E. coli in most samples. It is concluded that the honey antibacterial characteristics are influenced not only by extrinsic factors, but also intrinsic factors, providing characteristics that together provide honey changes in the expression of antimicrobial activity.