Avaliação das propriedades antimicrobianas de nanopartículas de óxido de zinco

Abstract

In this study, zinc oxide nanoparticles were synthesized via two different routes involving the thermal decomposition of layered hydroxy salts (LHS), with the aim of evaluating their structural properties and antimicrobial potential for future application in water-based acrylic paints. The resulting nanoparticles were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). These analyses enabled the characterization and determination of the average size of the crystallites formed at the nanoscale. Antimicrobial activity was assessed against Escherichia coli, Salmonella enterica typhimurium, and Candida tropicalis using 96-well plate assays with resazurin as a cell viability indicator. The results demonstrated that both samples exhibited antimicrobial activity showing greater efficacy against the yeast Candida tropicalis with the HDDS sample displaying the highest inhibition potential.