Síntese da dibenzalacetona substituída

Abstract

This study aimed to synthesize an ortho-nitro substituted dibenzalacetone through crossed aldol condensation under acidic and basic catalysis. Three experimental routes were tested, varying solvents and catalysts, and the products were characterized by ¹H and ¹³C NMR spectroscopy. The results showed that, under acidic conditions in ethanol, the major reaction pathway led to the formation of acetals instead of the expected α,β-unsaturated compound, due to competitive reactions with the solvent. The spectroscopic analysis confirmed the presence of aromatic fragments and acetalic groups. Although the target compound was not obtained, this work highlights the experimental challenges involved and provides insights for improving synthesis protocols in future studies.