Importância da padronização de procedimentos operacionais em bioprocessos como fator de eficiência: uma revisão

Abstract

This study aimed to examine the relevance of the standardization of Standard Operating Procedures (SOPs) in bioprocesses, emphasizing their role as a crucial element for operational efficiency and the reliability of industrial outcomes. The research was conducted through a literature review, gathering theoretical and practical contributions from authors who discuss the benefits, challenges, and future perspectives of using SOPs in industrial biotechnology. The study showed that standardization improves consistency, safety, and traceability, as well as simplifies audit and certification processes, optimizes team training, and integrates different sectors. On the other hand, obstacles such as cultural resistance to change, challenges in document updates, and failures in monitoring the implementation of procedures were identified. The analysis of the references suggests that digitalization and automation in SOP management are promising strategies to overcome these obstacles, encouraging innovation and continuous development. It was concluded that SOPs are fundamental strategic tools to ensure quality, regulatory compliance, and sustainability in industrial bioprocesses.