Efeitos adversos e colaterais das diferentes vacinas para COVID-19: uma revisão bibliográfica sistemática

Abstract

The Severe Acute Respiratory Syndrome Coronavirus 2, also known as COVID-19, impacted the world for approximately two years, affecting several crucial areas of human life. In addition to its effects on the economy and social leisure, the virus caused the deaths of thousands of people and forced global social isolation, a situation that was only reversed after worldwide vaccination. Although the vaccines brought relief to the situation, adverse effects have been associated with their administration, ranging from mild, such as pain and redness at the injection site, to severe and rare, such as Guillain-Barré Syndrome. These reactions may vary depending on the technology used in vaccine production, such as genetic, vector-based, protein-based and viral technologies. A systematic review was conducted using studies found in the Science Direct, Scopus, and PubMed databases, including a total of 46 articles relating adverse effects to the vaccines involved. It was concluded that the viral technology vaccine CoronaVac had the fewest reports of adverse effects, in contrast to the genetic technology vaccines, which had the highest number of reported adverse effects.