Aplicação de métodos cromatográficos na detecção de contaminantes emergentes oriundos de fármacos em águas: revisão sistemática da literatura

Abstract

The consumption of pharmaceutical products has experienced a significant increase, which raises a growing environmental concern related to the presence of emerging contaminants from pharmaceuticals present in different water sources. The techniques used in effluent treatment plants are ineffective in removing these contaminants. Therefore, the application of chromatographic techniques plays a crucial role in the identification and quantification of these residual drugs. Within the scope of this monograph, the main objective is to review the chromatographic methods used to detect and quantify drug residues, in addition to evaluating the effectiveness of these methods. This will be done by means of a systematic literature review, using the Prisma method, multicriteria approaches, the Snowball method and scientometrics. The database will be fed by articles from the Web of Science and Science Direct, containing the relevant keywords. The expected results include a solid basis for selecting the most appropriate chromatographic methods for the specific needs of residual drug analysis, promoting advances in environmental research and effluent treatment.