Complexos de európio (III) em aplicações biomédicas: uma descrição da literatura

Abstract

Organic-inorganic hybrid materials containing europium(III) have been attracting increasing attention due to the combination of their magnetic and optical properties. Because of their long luminescent lifetime, high thermal and chemical stability, they show enormous potential for biomedical applications, being studied for bioimaging, biological sensors, and controlled drug delivery systems. The reactivity of these complexes with various ligands results in a variety of structural species with significant biological activities. With the appropriate and careful choice of ligands, it is possible to enhance the stability and structural integrity of these complexes. This work explores the most recent studies and promising advances of europium(III) ion coordination compounds, highlighting their innovative role in disease diagnosis and monitoring. In this way, the review is based on relevant publications from specialized journals, with criteria focused on the technological innovations of the last ten years of studies on europium(III) complexes in biomedical applications. The most commonly used ligands, the functionalization strategies of these compounds, their extraordinary properties, and the challenges to make them even more efficient and viable in practice were discussed. Furthermore, some results already achieved and the perspectives that make these materials so promising for the future of medicine were presented. This study not only reinforces the relevance of this topic but also points out new research possibilities that can transform the biomedical field, exploring trends that may overcome the limitations of traditional diagnostics, offering more effective and safer alternatives.