Procedimentos e rotina para tecnólogos em radiologia na realização de exames de próstata em PET/CT utilizando 68Ga-PSMA-11 E 18F-PSMA-1007

Abstract

Prostate cancer is the most common malignancy among men, accounting for about a third of male cancer cases. In the year 2021, there were 16,055 deaths as a result of the disease in Brazil, corresponding to 44 deaths per day. However, early diagnosis provides a greater chance of cure and increased survival. Prostate-specific membrane antigen (PSMA) is a protein expressed in the prostate cell membrane, which has been shown to be an excellent marker for a cell type present in prostate cancer. The 68Ga and 18F radioisotopes, when combined with PSMA, become excellent radiopharmaceuticals in the diagnosis of prostate cancer by PET-CT, with remarkable clinical value for patients in the primary and secondary stages of prostate cancer. Nuclear medicine is a medical area that makes direct use of radioactive materials (unsealed sources), and it is extremely important that the hired professional has the knowledge about how to perform his duties safely. However, due to few internship opportunities and scarce materials on the area, the execution of a work that gathers theoretical and practical information about the routine of the technologist in an examination such as the prostate in PET/CT would be of great value, providing greater understanding of these professionals regarding their day-to-day work duties, and how to perform them in the best way. Therefore, the present study was elaborated from the practical observation of routine PET/CT exams, in addition to the study of the main CNEN norms referring to the area, articles and academic books for the theoretical basis, thus concluding its success in the creation of an accessible material that makes it possible to elucidate the routine of prostate exams in PET/CT.