Panorama dos MicroRNAs como biomarcadores na investigação do câncer de mama

Abstract

Breast Breast cancer is one of the most prevalent neoplasms among women worldwide, representing a significant challenge for public health due to the continuous increase in the incidence of this disease. This study aims to highlight microRNAs (miRNAs) as biomarkers in breast cancer research, with the intention of enriching the understanding of the advancement of scientific production, trends, and promoting the expansion of knowledge. Considering that these molecules play a crucial role in various stages of tumoral development, this research seeks to contribute to a deeper analysis in this area. As methodology, cienciometric analyses were employed using the Web of Science (WoS) / Core Collection database. After data refinement, they were exported to the Biblioshine program for the classification of works, considering quality index, authors, number of citations, and distributions among countries. The results revealed a significant interaction among countries, authors, and works published in this thematic area. The identification of molecular markers with prognostic value emerged as a crucial point, highlighting microRNAs as promising biomarkers in studies related to breast cancer. Thus, miRNAs emerge as a promising tool to enhance the detection, prognosis, and treatment of breast cancer. Their potential to positively impact clinical outcomes and public health associated with this challenging disease is considerable, suggesting a promising perspective for the advancement in the approach and management of breast cancer on a global scale.