Estudo das aplicações de modelos de liberação em têxteis funcionais

Abstract

Biofunctional fabrics appeared on the market in order to add additional functionalities to fabrics, since textiles can have microcapsules that are capable of constantly releasing doses of drugs or essential oils, always maintaining the dosage. Thus, these devices manage to control the release from the microencapsulation, which are divided into mononuclear, polynuclear or matrix. In this way, the release rates of substances can be calculated from mathematical models, which are able to help in the formulation of effective drugs and more accurate dosages. The present study proposed to analyze the controlled release in biofunctional tissues, from experimental data through the application of mathematical models, in order to obtain a profile of release kinetics. Based on these equations, it was possible to verify which mathematical model best fitted the evaluated experiments, carried out previously by the Apucarana innovation center, in which it was found that the Higuchi and Korsmeyer-Peppas models in linear form presented a higher correlation coefficient than the other models even compared with the articles analyzed in the work, in this way, it can be seen that in this work the linear form presented good results. However, it should be taken into account that non-linear models present a better explanation because they consider several variables that influence the time of controlled release.