Análise do fracionamento de compostos por meio de solventes eutéticos profundos naturais utilizando o simulador computacional DWSIM

Abstract

This study presents the simulation of the fractionation process of phenolic compounds and flavonoids from the unconventional plant Stachys bizantina, commonly known as peixinho da horta, using natural deep eutectic solvents (NADES). Considering the search for solvents that are less harmful to the environment and safe for health, the project aims to compare the extraction and fractionation process of these compounds using natural deep eutectic solvents through simulation. Studies on the use of choline chloride and glycerol as NADES have provided information about their physical properties and behavior. However, some essential information, such as critical temperature and pressure, has not been reported in the scientific literature and is not available in reliable databases. Despite this fact, experimental data were collected for the simulation of the choline chloride and glycerol process with 10%, 25%, and 50% water. However, the results were not satisfactory for the liquid-liquid extraction with the entry of phenolic compounds and flavonoids, as the results did not change at the mixer outlet, leading to the conclusion that simulating the process from the extract of the unconventional plant Stachys bizantina is not possible.