Mayaro vírus: epidemiologia e aspectos moleculares

Abstract

The Mayaro vírus (MAYV) was isolated for the first time in Trinidad and Tobago in 1954. It is a single-stranded (+) RNA virus, belonging to the Togaviridae family, Alphavirus genus. Its clinical symptoms are similar to those of other arboviruses, such as dengue (DENV), Chikungunya (CHIK) and zika (ZIKAV). The term “ChikDenMaZiK” has for suspected cases of these diseases. The majority of the population has never been exposed to the virus before. With the territorial expansion of vectors, MAYV has a vast potential to become a public health problem. However, with previous experience with other arboviruses, vector control has not proved to be an efficient way of spreading the disease, it is necessary to find other alternatives that contain the possible expansion of the disease. This work aims to elucidate the importance of further studies and investments for a better understanding of arboviruses that are neglected. Surveys were carried out in the WoS (Web of Science) database about the scientific production for the Mayaro virus and also a phylogenetic analysis of the complete genomic sequences deposited in GenBank. Our results show a lack of knowledge about this virus, leading to low specific diagnosis and positive case notification rates, generating a vicious cycle. Supporting knowledge of viral dynamics and correct diagnosis enables the creation of effective public policies.