Citotoxicidade e genotoxicidade do corante alimentar azul jeans a tecido de intensa proliferação celular

Abstract

A Blue Jeans dye is composed of Patent Blue and Fast Green dye. This mix of additives is used in various foods, such as in the delivery of cakes and sweets for parties. studies in the literature have evaluated the toxicity of these two triphenylmethane dyes some information on toxicity, however, these microingredients are not associated with each other. Thus, the objective is to evaluate the cytotoxicity and genotoxicity of Azul Jeans in powder forms, at 5 g/L and 0.25 g/L, and liquid, at 1 ml/L and 0.5 ml/L, in all origins of L. strain products in which they were manufactured in accordance with use cells of all products supplied in the products. The Azul Jeans brand was chosen because it is the most commercialized in the south and southeast regions of Brazil. For each consumption, use three onion bulbs, which were previously rooted in distilled water. Before placing the rooted onions in contact with their unique solutions, roots were collected to control the bulb itself. Then, the roots were identified for 2 hours in a row in contact with their 4 roots for 2 specific hours, where 2 roots every 2 hours were identified. After these two exposure times, the meristematic regionsof each bulb were highlighted for the preparation of slides. Slides were clarified as 40x objectives and 9.00 cells were evaluated for each view. The data obtained were analyzed by the Scott-Knott test (p < 0.05). The two issues in terms of the toxicity relationship of the content mix, in liquid form, caused exposure of origins, inhibiting the significant form of cell division in the. However, they did not induce the formation of cellular changes in a significant number, if not genotoxic. The results obtained,although preliminary, that associate the cellular level and the green blue dyes are fastin potential to cause intense tissues of toxic substances have cellular patents at the cellular level.